SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Nov 19, 2024--

Neuron23® Inc., a clinical-stage biotechnology company focused on developing­­ precision medicines for genetically defined neurological and immunological diseases, today unveiled details around its global ­­Phase 2 NEULARK clinical trial of NEU-411, a brain-penetrant, potent and selective inhibitor of LRRK2, in people with early Parkinson's disease (PD). The NEULARK trial represents a significant advancement in precision medicine, utilizing a state-of-the-art digital biomarker and patient stratification approach to identify individuals with LRRK2-driven PD who may be most likely to respond to treatment with NEU-411. While LRRK2 mutations are the most common cause of familial PD, representing 2% of the patient population, it is estimated that up to 30% of people with PD have LRRK2-driven disease.

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